CHARACTERIZATION OF INFLUENZA A VIRUS INDUCED TRANSPOSONS REVEALS A SUBGROUP OF TRANSPOSONS LIKELY POSSESSING THE REGULATORY ROLE AS ERNAS

Characterization of influenza A virus induced transposons reveals a subgroup of transposons likely possessing the regulatory role as eRNAs

Abstract Although many studies have observed genome-wide host transposon expression alteration during viral infection, the mechanisms of induction and the impact on the host remain unclear.Utilizing recently published influenza A virus (IAV) time series data and ENCODE functional genomics Office data, we characterized virus induced host differentia

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Enhancing chemoimmunotherapy for colorectal cancer with paclitaxel and alantolactone via CD44-Targeted nanoparticles: A STAT3 signaling pathway modulation approach

Chemoimmunotherapy has the potential Pump Inlet Seal to enhance chemotherapy and modulate the immunosuppressive tumor microenvironment by activating immunogenic cell death (ICD), making it a promising strategy for clinical application.Alantolactone (A) was found to augment the anticancer efficacy of paclitaxel (P) at a molar ratio of 1:0.5 (P:A) th

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